MDL, a company within the Genesis Biotechnology Group, is located in “Einstein’s Alley,” the research and technology corridor in

Only available through MDL, the HPV-16 Status reflex test makes available unique molecular testing that supplements the information provided by HPV Type-Detect® assay. It provides an integrated view of three factors reported to be associated with the development of HPV-16-related cervical dysplasia and cervical cancer.

High-risk human papillomaviruses (HPV) are found in almost all cervical tumors and are therefore considered a causative factor of cervical cancer. However, most cervical intraepithelial lesions caused by high-risk HPV are known to spontaneously regress. This suggests that, although a causative factor, high-risk HPV infection does not independently cause cervical cancer. Therefore, it is important to consider additional factors of HPV-16 that play a role in the progression of premalignant cervical lesions. Many studies have identified HPV-related markers that can predict the progression of cervical intraepithelial lesions and cervical cancer. The markers include, but are not limited to, HPV type, HPV integration status, and HPV viral load.

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